谱析（上海）生物科技有限公司优势供应：E. coli Gyrase Cleavage Assay Kits
2019/10/11 14:48:56
这导致细胞死亡，这是喹诺酮类药物，如纳立二酸和环丙沙星作用背后的机制。卵裂分析在确定潜在药物是否通过这一机制起作用时特别有用。这些试剂盒是专门为裂解反应设计的。除了酶和线性化的pBR322标记外，它们还包含超螺旋的pBR322 DNA底物、DNA裂解反应所需的分析和稀释缓冲液。解理特定的酶可单独要求。
Some drugs interrupt the DNA breakage-reunion step of the gyrase reaction. This leads to cell death and it is the mechanism behind the action of the quinolones such as nalidixic acid and ciprofloxacin. Cleavage assays are particularly useful in determining if a potential drug acts by this mechanism.These kits are designed specifically for cleavage reactions. They contain the supercoiled pBR322 DNA substrate and the Assay and Dilution buffers required for DNA cleavage reactions in addition to the enzyme and linearised pBR322 marker.
Cleavage specific enzyme available separately on request.
优势供应产品：
| Cat No. | Product | Product description |
| GCK001 | E.coli Gyrase Cleavage Kit 1 |
100 U of E. coli gyrase and 50 µg of supercoiled DNA |
| GCK002 | E.coli Gyrase Cleavage Kit 2 |
500 U of E. coli gyrase and 250 µg of supercoiled DNA |
| GCK003 | E.coli Gyrase Cleavage Kit 3 |
1000 U of E. coli gyrase and 500 µg of supercoiled DNA |
| GCK004 | E.coli Gyrase Cleavage Kit 4 |
2000 U of E. coli gyrase and 1 mg of supercoiled DNA |
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