谱析(上海)生物科技有限公司提供——Antiasthmatics in Plasma 质谱诊断方案
2022/3/4 15:31:40
谱析(上海)生物科技有限公司提供——Antiasthmatics in Plasma 质谱诊断方案
一、说明
Theophylline, theobromine and caffeine are termed as methylxanthines and are used in the management of asthma bronchiale. Methylxanthines produce a relaxation of the bronchial smooth muscle and thus are helping to open up constricted airways (bronchodilators). The drug absorption and metabolism may be affected by many factors, including co-medication with other drugs (e.g. several AEDs). A monitoring of the plasma level is therefore essential to ensure that therapeutic, but not toxic drug doses are applied. The RECIPE ClinRep@ Complete Kit features simple and quick sample preparation, a cost efficient analysis and ensures reliableres.
二、产品优势
(1)Simultaneous determination of 3 methylxanthines
(2)Simple and quick sample preparation
三、测试数据
Linearity: 1.3 - 50 mg/1
Recovery: approx. 70 %
LOD: Theophylline: 0.8 mg/l
Theobromine: 0.6 mg/l
Caffeine: 0.6 mg/l
LLOQ: Theophylline: 1.7 mg/l
Theobromine: 1.3 mg/l
Caffeine: 1.4 mg/l
Intraassay precision: 2.5 %
Interassay precision: 1.7 %
四、高效液相色谱参数
Pump: isocratic pump, flow rate: 1.5 ml/min
Injection volume: 20 μI
Injection interval: 8 min
UV/VIS-Detector: 273 nm
HPLC-Thermostat: 37°C
五、样品制备
六、订购信息
更多产品请咨询谱析(上海)生物科技有限公司。
网址: www.xiyuan-bio.com
电话:021-58116080
手机:17717017426 陈经理 18019263206 陆经理
谱析(上海)生物科技有限公司,您实验室试剂供应专家,欢迎咨询详谈。
一、说明
Theophylline, theobromine and caffeine are termed as methylxanthines and are used in the management of asthma bronchiale. Methylxanthines produce a relaxation of the bronchial smooth muscle and thus are helping to open up constricted airways (bronchodilators). The drug absorption and metabolism may be affected by many factors, including co-medication with other drugs (e.g. several AEDs). A monitoring of the plasma level is therefore essential to ensure that therapeutic, but not toxic drug doses are applied. The RECIPE ClinRep@ Complete Kit features simple and quick sample preparation, a cost efficient analysis and ensures reliableres.
二、产品优势
(1)Simultaneous determination of 3 methylxanthines
(2)Simple and quick sample preparation
三、测试数据
Linearity: 1.3 - 50 mg/1
Recovery: approx. 70 %
LOD: Theophylline: 0.8 mg/l
Theobromine: 0.6 mg/l
Caffeine: 0.6 mg/l
LLOQ: Theophylline: 1.7 mg/l
Theobromine: 1.3 mg/l
Caffeine: 1.4 mg/l
Intraassay precision: 2.5 %
Interassay precision: 1.7 %
四、高效液相色谱参数
Pump: isocratic pump, flow rate: 1.5 ml/min
Injection volume: 20 μI
Injection interval: 8 min
UV/VIS-Detector: 273 nm
HPLC-Thermostat: 37°C
五、样品制备
六、订购信息
更多产品请咨询谱析(上海)生物科技有限公司。
网址: www.xiyuan-bio.com
电话:021-58116080
手机:17717017426 陈经理 18019263206 陆经理
谱析(上海)生物科技有限公司,您实验室试剂供应专家,欢迎咨询详谈。