谱析（上海）生物科技有限公司提供——Amiodarone in Plasma 质谱诊断方案
 
一、说明
Cardiac arrhythmias are major causes of morbidity and mortality throughout the world. Arrhythmias are controlled by medication of several drugs, such as amiodarone, an antiarrhythmic agent that helps to stabilise the normal rhythm of the heart. The resorption rate and the biological availability of amiodarone is low and extremely variable. The therapy therefore requires a close monitoring for the adjustment of the drug dosage. The RECIPE ClinRep@ Complete Kit allows a quick, sensitive and reliable determination of amiodarone and the main metabolite desethylamiodarone. The sample preparation consists of a simple precipitation step. 
 
二、产品优势
（1）Simple and quick sample preparation
（2）Linearity over a wide range
（3）Short run time
 
三、测试数据
Linearity:                  0.1 - 10 μg/ml
Recovery:                   95 - 105 %
LOD:                        0.07 μg/ml
LLOQ:                       0.1 μg/ml
Intraassay precision:      Amiodarone:         2.1%,
                            Desethylamiod.:     2.5 %
Interassay precision:       Amiodarone:         4.0%, 
                            Desethylamiod.:     4.2 %
 
四、高效液相色谱参数
Pump:                       isocratic pump, flow rate: 0.8 ml/min
Injection volume:           20 μI
Injection interval:         8 min
UV/VIS-Detector:            255 nm
HPLC-Thermostat:            30°C 
 
五、样品制备
 
 
 
六、订购信息
 

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