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2022/3/4 9:39:55
谱析(上海)生物科技有限公司提供——Hemoglobin Variants and ß-Thalassemia Screening in Whole Blood 质谱诊断方案
 
一、说明
Defects in genes, which are responsible for the synthesis of the hemoglobin molecule, result in a group of hereditary diseases termed as "hemoglobinopathies". Depending on the molecular defect, hemoglobinopathies may be classified in "structural hemoglobin variants" and in "thalassemias". This test kit allows a reliable separation and identification of the common and clinically significant hemoglobin variants. For B-thalassemia screening the kit ensures an exact quantification of HbF and HbA2. A ready for use test solution (containing: HbA1c, HbF, HbAO, HbE, HbA2, HbD, Hbs, HbC), a hemolysate calibrator (containing: HbF, HbA2) as well as hemolysate controls in two levels of concentration are available for quality assurance.
 
二、产品优势
(1)可靠地分离和定量HbA2和HbF
(2)Hbs、HbC、HbE和HbD的安全识别
(3)可提供测试溶液,校准器和控制材料
 
三、测试数据
Intraassay precision:      1.0 - 3.3 % (HbF)
0.6 - 3.6 % (HbA2)
Interassay precision:       2.1 - 2.8% (HbF)     
0.7 - 2.4 (HbA2)
Dependence on total hemoglobin:
The HbF and HbA2 values are independent on the amount of total hemoglobin in a range from 6-24 g/dl total hemoglobin. 
 
四、高效液相色谱参数
Pump:                       binary gradient pump
Flow rate:                  1.2 ml/min
Injection volume:           20 μl
Injection interval:         8 min
UV/VIS-Detector:            415 nm
HPLC-Thermostat:            23 °C
 
五、样品制备
 
 
 
六、订购信息
 

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